Fig. 5: Melatonin increases fatty acid oxidation in skeletal muscle.

A Muscle TG content. B H&E-stained skeletal muscle section. Scale bars = 100 μm. C mRNA expression of fatty acid oxidation-related genes in skeletal muscle. D Immunoblots of phosphorylated Th172 AMPK and AMPK in skeletal muscle. Data are mean ± SEM, n = 5–8. Significance was determined by one-way ANOVA. *p < 0.05, **p < 0.01 vs. NC + Veh mice; #p < 0.05, ##p < 0.01, vs. HFD + Veh mice.