Fig. 5: Effects of 24 h ADF on pubertal development in HFD-induced obese mice. | Nutrition & Diabetes

Fig. 5: Effects of 24 h ADF on pubertal development in HFD-induced obese mice.

From: Alternate-day fasting delays pubertal development in normal-weight mice but prevents high-fat diet-induced obesity and precocious puberty

Fig. 5

a Cumulative percentage of VO; b Average age at puberty onset; c Body weight at P34; d Body length at P34; e Uterine weight at P34; f Ovarian weight at P34; g Plasma levels of LH at P34; h Plasma levels of FSH at P34; i Plasma levels of E2 at P34; j Plasma levels of GH at P34; k Plasma levels of IGF-1 at P34; l Plasma levels of insulin at P34; m Plasma levels of leptin at P34. Data are presented as mean ± SEM, and p-values were calculated using the one-way ANOVA and the Kruskal–Wallis test. Due to differences in variance, the Kruskal–Wallis test did not indicate a significant difference in uterine weight between the Cntrl and HFD groups, but the Mann–Whitney test did (Supplementary Fig. 2). Each data point corresponds to an individual mouse. PND Postnatal days. The data represent three separate experiments.

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