Table 2 The mediatory role of sleep quality on the association between traditional healthy lifestyle and MAFLD-related outcomes.
Traditional healthy lifestyle | Unadjusted for sleep quality | Adjusted for sleep quality | Mediation proportion (%) (95%CI) | ||
|---|---|---|---|---|---|
Odds ratio (95%CI) | P for trend | Odds ratio (95%CI) | P for trend | ||
MAFLD | |||||
ISSCC | 0.004 | 0.011 | |||
3 to 4 healthy behaviors | 1 (reference) | 1 (reference) | Reference | ||
2 healthy behaviors | 1.39 (1.19–1.62) | 1.37 (1.18–1.60) | 4.66 (1.14–10.00) | ||
0 to 1 healthy behavior | 1.23 (0.98–1.55) | 1.19 (0.94–1.50) | 17.72 (7.04–72.00) | ||
US NHANES | 0.016 | 0.040 | |||
3 to 4 healthy behaviors | 1 (reference) | 1 (reference) | Reference | ||
2 healthy behaviors | 1.43 (1.06–1.94) | 1.39 (1.02–1.89) | 8.02 (3.77–14.00) | ||
0 to 1 healthy behavior | 1.60 (1.10–2.34) | 1.52 (1.01–2.29) | 10.88 (5.40–18.00) | ||
At-risk MASH in US NHANES | <0.001 | 0.002 | |||
3 to 4 healthy behaviors | 1 (reference) | 1 (reference) | Reference | ||
2 healthy behaviors | 1.74 (1.13–2.66) | 1.70 (1.06–2.72) | 9.88 (1.27–63.00) | ||
0 to 1 healthy behavior | 3.39 (2.01–5.71) | 3.11 (1.69–5.75) | 8.08 (2.02–19.00) | ||
Significant fibrosis in US NHANES | 0.156 | 0.364 | |||
3 to 4 healthy behaviors | 1 (reference) | 1 (reference) | Reference | ||
2 healthy behaviors | 1.19 (0.78–1.80) | 1.18 (0.71–1.93) | 13.13 (3.52–47.00) | ||
0 to 1 healthy behavior | 1.53 (0.84–2.77) | 1.38 (0.67–2.83) | 11.87 (1.68–40.00) | ||
