Table 1 Changes of dietary measures in patients subjected to metformin or acarbose groups at baseline, 24 weeks and 48 weeks.

From: Longitudinal associations of dietary fiber and its source with 48-week weight loss maintenance, cardiometabolic risk factors and glycemic status under metformin or acarbose treatment: a secondary analysis of the March randomized trial

Dietary measures

Baseline

24-week treatment

48-week treatment

P value

Acarbose

    

 Total fiber (g/d)

7.89 (5.33, 11.68)

7.46 (5.13, 10.94)

7.46 (5.38, 10.06)

0.319

 Fruit fiber (g/d)

0 (0. 0.28)

0 (0, 0.73)

0 (0, 0.46)

0.423

 Vegetable fiber (g/d)

2.27 (1.39, 4.03)

2.09 (1.23, 3.13)

2.09 (1.39, 3.48)

0.233

 Legume fiber (g/d)

0 (0, 0.41)

0 (0, 0.55)

0 (0, 0.20)b

0.001c

 Whole grain fiber (g/d)

0 (0, 0.80)

0 (0, 0.80)

0 (0, 0.44)

0.956

 Carbohydrate-to-fiber ratio

28.41 (20.58, 37.67)

26.59 (18.00, 35.05)

30.20 (21.86, 37.56)c

0.002c

Metformin

    

 Total fiber (g/d)

8.89 (5.89, 11.84)

8.14 (5.07, 12.20)

8.04 (5.55, 11.19)

0.619

 Fruit fiber (g/d)

0 (0. 0.24)

0 (0, 0.91)

0 (0, 0.70)

0.013c

 Vegetable fiber (g/d)

2.36 (1.29, 4.18)

1.82 (1.21, 3.13)b

2.30 (1.39, 3.48)b

0.002c

 Legume fiber (g/d)

0 (0, 0.58)

0 (0, 0.40)

0 (0, 0.41)

0.133

 Whole grain fiber (g/d)

0 (0, 0.50)

0 (0, 0)

0 (0, 0)

0.786

 Carbohydrate-to-fiber ratio

26.29 (18.74, 34.33)

26.43 (18.18, 34.20)

29.16 (21.33, 35.76)ab

0.003c

  1. Data presented as median and interquartile range were tested by Friedman’s two-way analysis of variance by ranks test during three time periods (baseline, 24 weeks, and 48 weeks) in two treatment groups.
  2. aSignificant difference from Baseline (adjusted P < 0.05)
  3. bSignificant difference from 24-week treatment (adjusted P < 0.05)
  4. cSignificant difference from baseline to 48-week treatment (P < 0.05)