Table 1 Baseline characteristics of patients included in the study.

From: MiRNAs as biomarkers of nutritional therapy to achieve T2DM remission in patients with coronary heart disease: from the CORDIOPREV study

 

Low-fat diet

 

Mediterranean diet

  

Paramenters

Non-responders (n = 63)

Responders (n = 40)

p-Value (a)

Non-responders (n = 47)

Responders (n = 33)

p-Value (a)

p diet vs group (b)

Age (years)

59.6 ± 1.2

60.0 ± 1.5

0.850

58.8 ± 1.4

61.9 ± 1.4

0.123

0.325

Weight (kg)

89.1 ± 1.6

78.7 ± 1.7

<0.001

87.6 ± 2.4

82.1 ± 2.0

0.103

0.223

Waist circumference (cm)

109 ± 1

100 ± 1

<0.001

107 ± 2

103 ± 2

0.104

0.081

BMI (kg/m2)

31.9 ± 0.5

29.5 ± 0.6

0.005

32.3 ± 0.7

30.3 ± 0.7

0.057

0.752

Systolic Blood Pressure (mmHg)

141 ± 2

133 ± 3

0.040

134 ± 3

142 ± 4

0.080

0.007*

Diastolic Blood Pressure (mmHg)

77.1 ± 1.4

75.1 ± 2.1

0.413

77.1 ± 1.4

78.4 ± 2.3

0.638

0.369

Triglycerides (mg/dL)

145 ± 8

138 ± 11

0.862

145 ± 8

112 ± 8

0.009

0.170

C-reactive protein (mg/dL)

2.82 ± 0.29

2.78 ± 0.34

0.930

2.69 ± 0.29

2.48 ± 0.33

0.636

0.794

LDL-c (mg/dL)

93.1 ± 3.3

87.9 ± 4.2

0.334

93.5 ± 4.4

90.6 ± 3.5

0.634

0.776

HDL-c (mg/dL)

40.5 ± 1.1

43.7 ± 2.1

0.151

41.1 ± 1.3

42.0 ± 1.5

0.627

0.460

Glucose (mg/dL)

121 ± 4

99 ± 2

<0.001

115 ± 3

99 ± 3

<0.001

0.417

HbA1c (%)

6.86 ± 0.13

6.43 ± 0.11

0.023

6.70 ± 0.08

6.65 ± 0.13

0.704

0.127

Insulin (mU/L)

12.4 ± 1.0

10.2 ± 1.1

0.128

14.8 ± 2.3

8.2 ± 1.2

0.026

0.159

  1. Data represent the mean ± SEM. The analysis was performed using (a) ONE-WAY ANOVA to evaluate differences between groups and (b) univariate general linear model for each variable to evaluate the diet vs group interaction. p < 0.05 was considered statistically significant. Responders patients who reverted from type 2 diabetes after 60 months of dietary intervention, Non-Responders patients who remained with type 2 diabetes after the follow-up period, BMI body mass index, LDL-c low density lipoproteins, HDL-c high density lipoproteins.
  2. * Significant p value < 0.05.