Table 1 Enriched pathways in 46 commonly differentially expressed genes from RNA-Seq and CCLE microarray data
From: Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner
ID | Term | P-value | Genes |
---|---|---|---|
GO:0016055 | Wnt receptor signaling pathway | 0.0009 | WNT5A, TBL1XR1, DKK1, TLE2 |
GO:0009411 | Response to UV | 0.0009 | ERCC8, HUS1, GTF2H2 |
GO:0009628 | Response to abiotic stimulus | 0.0011 | ARSB, ERCC8, SNN, HUS1, COL3A1, GTF2H2 |
GO:0035113 | Embryonic appendage morphogenesis | 0.0028 | WNT5A, DKK1, SMARCA4 |
GO:0030326 | Embryonic limb morphogenesis | 0.0028 | WNT5A, DKK1, SMARCA4 |
GO:0009314 | Response to radiation | 0.0040 | ERCC8, HUS1, COL3A1, GTF2H2 |
GO:0035107 | Appendage morphogenesis | 0.0041 | WNT5A, DKK1, SMARCA4 |
GO:0035108 | Limb morphogenesis | 0.0041 | WNT5A, DKK1, SMARCA4 |
GO:0048736 | Appendage development | 0.0045 | WNT5A, DKK1, SMARCA4 |
GO:0060173 | Limb development | 0.0045 | WNT5A, DKK1, SMARCA4 |
REACT_216 | DNA repair | 0.0060 | ERCC8, RAD50, GTF2H2 |
GO:0051052 | Regulation of DNA metabolic process | 0.0060 | ERCC8, HUS1, RAD50 |
GO:0033554 | Cellular response to stress | 0.0094 | SLC11A2, WNT5A, ERCC8, HUS1, RAD50, GTF2H2 |
GO:0009416 | Response to light stimulus | 0.0100 | ERCC8, HUS1, GTF2H2 |