Fig. 8 | Oncogene

Fig. 8

From: Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10

Fig. 8

MiR-23a directly targets zebrafish tsga10. a The sequences of hsa-miR-23a and dre-miR-23a. Seed sequences are shown in a dashed line box. b Schematic of the predicted miR-23a binding sequence in tsga10-3′-UTR. c Overexpression of miR-23a (miR-23a-pre) reduced tsga10-3′-UTR luciferase activity in HUVECs. One-way ANOVA. d miR-23a-precursor injection reduced the mCherry levels in mCherry-tsga10-3′-UTR sensor, whereas no change in EGFP was observed. In the mutant sensor, mcherry levels were not reduced

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