Fig. 2
From: NGR (Asn-Gly-Arg)-targeted delivery of coagulase to tumor vasculature arrests cancer cell growth
Molecular dynamic studies of tCoa-NGR proteins in silico. a Protein structure of tCoa-NGR. b 3D structure of tCoa-NGR. Helical structure of tCoa-NGR within its two important domains. c Molecular dynamic simulation of tCoa-NGR-prothrombin complex. d Insertion of tCoa N-termius into prothrombin. e Interactions of Arg75 of prothrombin with Glu213 and Tyr48 of tCoa. f Interactions between Lys81 of prothrombin and Asn282 of tCoa-NGR. g Interactions between basic residues of prothrombin and acidic residues of tCoa-NGR
