Fig. 4
From: NGR (Asn-Gly-Arg)-targeted delivery of coagulase to tumor vasculature arrests cancer cell growth

Tracing fluorescently labeled tCoa-NGR proteins in vivo. a Tumor-free mice injected with saline as control. Mice bearing PC3 prostate cancer xenografts were injected with either (b) tCoa labeled with FITC or (c) tCoa-NGR labeled with FITC (n = 6). Selective accumulation of targeted fusion protein to tumor neovasculature was assessed by an in vivo imaging system