Fig. 4

Analysis of messenger RNA (mRNA) transcripts present in PC3-EVs identifies an enrichment of genes involved in polymerase III transcription. a Cell component analysis demonstrates a significant enrichment of genes involved in nuclear functions (Nucleus, Nucleolus and Centrosome) and cytoplasmic functions involved in translation (ribosomes) and endosomal vesicle formation (exosomes). b Biological pathway analysis indicates a significant enrichment of process involved in protein translation (top 10 shown, full analysis detailed in Supplementary Table 2)