Fig. 7 | Oncogene

Fig. 7

From: Epigenetic reprogramming of primary pancreatic cancer cells counteracts their in vivo tumourigenicity

Fig. 7

Model of cancer reprogramming and subsequent differentiation in 247-REP cells. Schematic illustration of the correlation between epigenetic modifiers, stemness and EMT genes following reprogramming in PDAC 247 cells. The sequential introduction of the episomal vectors leads to reprogramming of 247-PDAC cells and subsequent differentiation and loss of tumourigenicity (see discussion for details)

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