Fig. 3: TTPAL promoted migration and invasion of GC cells.
From: TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling
A Representative images of wound healing assay revealed that ectopic expression of TTPAL promoted cell migration in BGC823 and MGC803 cells. B Representative images of matrigel invasion transwell assay revealed that ectopic expression of TTPAL promoted cell invasion in BGC823 and MGC803 cells. C Knockdown of TTPAL significantly inhibited migration ability. D Knockdown of TTPAL significantly decreased cell invasion ability. E TTPAL expression increased the levels of N-cadherin and Snail, and decreased E-cadherin level in BGC823 and MGC803 cells, while knockdown of TTPAL showed the opposite effect on these EMT markers.
