Fig. 3: Influence of FBP1 on the progression and chemosensitivity of ovarian cancer in vivo. | Oncogene

Fig. 3: Influence of FBP1 on the progression and chemosensitivity of ovarian cancer in vivo.

From: FBP1 regulates proliferation, metastasis, and chemoresistance by participating in C-MYC/STAT3 signaling axis in ovarian cancer

Fig. 3

A Representative luciferase image of nude mice bearing tumors formed by FBP1-overexpressing A2780 or SKOV3 cells or transfected with empty vector (Vec) or FBP1 (FBP1 OE) (n = 5). B Representative image of nude mice bearing tumors formed by A2780 and SKOV3 cells. C The average tumor volume after cisplatin treatment. D The average tumor weight after cisplatin treatment. E Gross image (left panels) and representative luciferase image (right panels) of the intraperitoneal dissemination of tumors formed by A2780 and SKOV3 cells expressing empty vector (Vec) or FBP1 (FBP1 OE). Red arrows show the position of tumors in the nude mice. F The average tumor weight after intraperitoneal injection. G Average body weight of mice after intraperitoneal injection. Error bars = 95% CIs. *P < 0.05, **P < 0.01.

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