Fig. 2: LNMAS inhibits cervical cancer cells metastasis and lymphangiogenesis in vitro.

A Representative RNA FISH images of LNMAS and β-actin in HeLa. Subcellular fractionation assays and qPCR analyses of LNMAS expression in the nucleus and cytoplasm of HeLa (B) and SiHa (C). Representative images of wound healing assays using SiHa and HeLa after overexpression (D) or knockdown (E) of LNMAS. Representative images of transwell assays using SiHa and HeLa after overexpression (F) or knockdown (G) of LNMAS. Representative images of HLEC tube formation assays using the conditioned media from SiHa and HeLa after overexpression (H) or knockdown (J) of LNMAS. Statistical significance was assessed by Student’s t test in D, F, H and one-way ANOVA test in E, G, J. Data are presented as mean ± SD, n = 3, *P < 0.05, **P < 0.01.