Fig. 6: Targeted methylation of CD147 inhibited NSCLC progression in vitro. | Oncogene

Fig. 6: Targeted methylation of CD147 inhibited NSCLC progression in vitro.

From: Active demethylation upregulates CD147 expression promoting non-small cell lung cancer invasion and metastasis

Fig. 6

A MTT assay was performed to detect the proliferation of NSCLC cells transfected with targeted methylation vector at the indicated time periods. *P < 0.05, **P < 0.01. Two-way repeated-measures ANOVA followed by Bonferroni test was used for statistical analysis. B Colony-formation assay was performed using cells after transfection as described. Colony numbers per well were counted. C Effects of targeted methylation of CD147 on the invasion and migration of NSCLC cells were detected using Transwell assay. D A wound-healing assay was performed using transfected NSCLC cells. *P < 0.05, **P < 0.01, one-way ANOVA followed by Dunnett’s test was used for statistical analysis in (B), (C) and (D).

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