Table 1 IL-36 family member Expression in Colon Tumour cells and Adjacent normal epithelial cells.

From: IL-36 signalling enhances a pro-tumorigenic phenotype in colon cancer cells with cancer cell growth restricted by administration of the IL-36R antagonist

  

0-negative

1-weak

2-moderate

3-strong

IL-36α

Adj. Normal

48 (73%)

16 (24%)

2 (3%)

0

Tumour

28 (42%)

18 (27%)

14 (21%)

6 (10%)

IL-36γ

Adj. Normal

40 (61%)

26 (39%)

0

0

Tumour

2 (3%)

18 (27%)

26 (39%)

20 (31%)

IL-36R

Adj. Normal

24 (36%)

42 (64%)

0

0

Tumour

3 (5%)

33 (50%)

20 (30%)

10 (15%)

  1. Tumour cells and adjacent normal epithelial cells were scored as negative, weak, moderate or strong, according to the intensity of IL-36α, IL-36γ and IL-36R expression. (n = 66). % represents the number of sections scored in the corresponding category as a percent of the total number of samples scored.
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