Fig. 8: PDGF-Rα/β inhibition by CP-673451 induces differentiation of glioblastoma cells via DUSP1/p38MAPK pathway activation.
From: PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling

Diagram of potential mechanism of action of CP-673451 in GBM cells.