Fig. 2: Differential protein expression in chemoresistant OS models. | Oncogene

Fig. 2: Differential protein expression in chemoresistant OS models.

From: The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review

Fig. 2

Protein expression data for in vitro studies was extracted into a data table and entered into R to develop a summary heatmap of expression grouped by distinct model. Proteins are organised from most (top) to least (bottom) investigated across different models. Models are ordered by the MAP agent used for generation. (Blue) Downregulated, (Red) Upregulated, (Grey) Unchanged with respect to each models’ corresponding parental cell line, (Black) unknown or ambiguous result signifying an area of potential research interest (number of studies = 13).

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