Fig. 6: Low protein expression of EIF4G2 targets KLC1 and KIF5B correlates with worse overall survival in EC patients. | Oncogene

Fig. 6: Low protein expression of EIF4G2 targets KLC1 and KIF5B correlates with worse overall survival in EC patients.

From: Loss of EIF4G2 mediates aggressiveness in distinct human endometrial cancer subpopulations with poor survival outcome in patients

Fig. 6

A FFPE tumor TMA sections from the 280 patients were immunostained for KLC1, KIF5B, CK and DAPI. Representative images of two patients are shown. Scale bar 100 µM. Overall survival of the 280 endometrial patients according to tumor (B, C) type, (D, E) stage, and (F, G) grade. KLC1 (B, D, F) and KIF5B (C, E, G) staining in CK positive cells was stratified according to high and low intensity levels compared to the calculated median, and overall survival was assessed by Kaplan–Meier statistics. Log rank P-val was determined for protein expression of each of these signatures. Paired comparison was calculated with FDR correction. *p < 0.05, ***p < 0.001.

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