Fig. 4: Sex-dependent differences in hematopoietic stem/progenitor cells from aging and long-lived BALB/c mice.
From: Sex-dependent differences in hematopoietic stem cell aging and leukemogenic potential
a Representative flow cytometry plots of bone marrow SPs from male and female BALB/c mice at different ages. b Frequencies of SP HSPCs in males vs females in 3-, 18- and 28-month (m)-old mice. Notice the scale difference between males and females. c, d Gating for the upper and lower SP fractions (c) and the percentage of upper and lower SP fractions within the total SP pool (d). e Frequencies of CD150+ and CD150- SP HSCs in males vs females in 3-, 18- and 28-month-old mice. f Distribution of CD150+ and CD150- cells within the SP pool in 28-month-old mice. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; ns, not significant. The error bars represent one standard deviation.
