Fig. 6: Slc7a5 regulates TCR signaling and the AhR metabolic pathway in TILs in mice.

A UMAP plot of major cell subpopulations isolated from orthotopic breast tumor-bearing mice, colored by identified cell clusters (right panel). B Dot plot of signaling pathway activation as identified by expression of gene signatures in the indicated cell subpopulations in WT and Slc7a5.TKO (KO) mice. C Violin plot of signaling pathway activation as identified by expression of gene signatures in the indicated cell subpopulations in WT and Slc7a5.TKO mice. Dot (D) and violin (E) plots of expression of the indicated genes in the indicated cell subpopulations in WT and Slc7a5.TKO mice.