Fig. 1: High secretion and overexpression of S100A11 in MPM.
From: Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma
a Concentration of secreted S100A11 in the culture media of various cell lines, as determined by ELISA. The secretion level of S100A11 in all MPM cell lines, except for 211H, is higher than that of NM. 211H MSTO-211H, NM normal mesothelial cell, LC lung cancer, GC gastric cancer, CRC colorectal cancer, BC breast cancer. b Protein level of S100A11 was higher in MPM cell lines, compared to NM. NM normal mesothelial cell. c Immunohistochemical analysis of S100A11 in surgically resected tissues from patients with MPM. The representative images of three MPM subtypes are shown. The pictures on the left show hematoxylin–eosin (HE)-stained images corresponding to the S100A11-stained images in the middle. Scale bars, 50 µm (positive and negative control) and 100 µm (clinical samples)
