Fig. 5: Secreted S100A11 exerts its important role in the proliferation of MPM cells via RAGE. | Oncogenesis

Fig. 5: Secreted S100A11 exerts its important role in the proliferation of MPM cells via RAGE.

From: Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma

Fig. 5

a RAGE protein expression in MPM cells. b Inhibition of RAGE signaling through sRAGE significantly suppressed the phosphorylation of STAT3 and MAPK induced by S100A11 recombinant protein. c The effect of sRAGE on the growth of MPM cells examined by MTT assay. Cell proliferation was significantly inhibited by sRAGE

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