Fig. 3: GST substrates. | Oncogenesis

Fig. 3: GST substrates.

From: Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases

Fig. 3

a First two steps of the metabolism of aflatoxin B1; b detoxification pathway of 4-hydroxynonenal involving GST; c GST-catalyzed conjugation of acrolein and subsequent trasnformation steps d enzymatic inactivation of cisplatin catalyzed by GSTs; e first step of the metabolic pathway of busulfan; f enzymatic inactivation of dichoroacetate leadind to glyoxylate

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