Fig. 4: CSE promotes renal CSCs stemness via upregulating SHH pathway. | Oncogenesis

Fig. 4: CSE promotes renal CSCs stemness via upregulating SHH pathway.

From: Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway

Fig. 4

a–c 786-O and ACHN tumorspheres were treated with 0.1% CSE with/without 10 mM Vismodegib for 5 days. a Western blotting analysis of SHH pathway proteins. b Images of tumorsphere formation. Bar, 100 μm. c The number of tumorspheres was calculated and normalized to control group. d Western blotting analysis of renal CSCs markers

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