Fig. 1
From: MUC13 contributes to rewiring of glucose metabolism in pancreatic cancer
MUC13 enhances glucose metabolism in PDAC cells. Expression of MUC13 shown by western blotting, lactate and glucose assay in MUC13-null Panc-1 (P-V) and stably expressing MUC13 (P-M13) cells (a) and in MUC13-null MiaPaca (M-V) and stably expressing MUC13 (M-M13) cells (b). Invasion assay performed in P-V and P-M13 (c) and M-V and M13 cells (d) after treatment with lactate (2 mM) and 2-DG (10 mM). Images were captured after 24 h and the relative number of invasive cells was quantified. Wound-healing (scratch) assay performed in P-V and P-M13 (e) and M-V and M13 cells (f) after the treatment with lactate (2 mM) and 2-DG (10 mM). The images were captured at 0 h and 24 h. n = 3; *p < 0.05
