Fig. 2: Phenotypic and functional characteristics of PD1+ macrophages in GC tissue. | Oncogenesis

Fig. 2: Phenotypic and functional characteristics of PD1+ macrophages in GC tissue.

From: Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression

Fig. 2

a–d Flow cytometry analysis was performed to analyze the phenotypic characteristics of PD1−, and PD1+ macrophages from GC tissues. a Analysis of representative markers expressed by tumor-infiltrating PD1−, and PD1+ macrophages. b, c Results represent the mean of four independent experiments. e, f Analysis of IL-10, IL-12, and CCL1 expression in PD1−, and PD1+ macrophages derived from GC tissue by q-PCR (e) and ELISA (f). g, h Phagocytic ability analysis of PD1−, and PD1+ macrophages derived from GC tissue by flow cytometry. Representative flow cytometry plots are shown in (g). h Results represent the mean of five independent experiments. *P < 0.05, **P < 0.01, and ***P < 0.001 (Student's t test)

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