Fig. 5: LGR5 regulates proliferation and invasion through Wnt/β-catenin signaling in BGC823 and SGC7901 cells. | Oncogenesis

Fig. 5: LGR5 regulates proliferation and invasion through Wnt/β-catenin signaling in BGC823 and SGC7901 cells.

From: LGR5 regulates gastric adenocarcinoma cell proliferation and invasion via activating Wnt signaling pathway

Fig. 5

Cells were transiently transfected with corresponding plasmids. Meanwhile, LGR5 overexpressing cells were treated with Wnt inhibitor C59 and LGR5-knowdown cells were treated with activator Wnt3a. Twenty-four hours after treatment, the cells were examined in the wound healing assay. MTT assays were also started 24 h after treatment. MTT assay (a, b) and wound healing assay (cf) were performed as described in Methods. **P< 0.01

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