Fig. 5: Low CUL5 expression is associated with impaired survival in patients with ccRCC. | Oncogenesis

Fig. 5: Low CUL5 expression is associated with impaired survival in patients with ccRCC.

From: Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability

Fig. 5

a Kaplan–Meier survival curve of KIRC-TCGA patients showing low CUL5 gene expression (1st quartile, blue), which is associated with significantly worse overall overall survival when compared to patients with high CUL5 expression levels (4th quartile, red). Second and third quartiles are shown combined in green. b Kaplan–Meier survival curve of KIRC-TCGA patients with a CUL5 chromosomal deletion in comparison to patients with no loss of the CUL5 gene. Note the significantly worse overall survival in patients with a CUL5 deletion

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