Fig. 6: Growth regulation of breast cancer cells by miR590-5p. | Oncogenesis

Fig. 6: Growth regulation of breast cancer cells by miR590-5p.

From: Estrogen receptor-α regulation of microRNA-590 targets FAM171A1—a modifier of breast cancer invasiveness

Fig. 6

a, b Effect of miR590-5p mimic and LNA treatments on the growth of MDA-MB-231 and SUM149 as assessed by colony formation assay; quantification on top. c, d Quantification of the tumorspheres formed upon miR-590-5p mimic and LNA treatments in MDA-MB-231 and SUM149 cells; *p-value < 0.05, one-way ANOVA; **p-value < 0.005. e Working model showing the summary of the regulation of the ERα–miR590-5p–FAM171A1 axis in breast cancer cells. Experiments were performed in two biological replicates each with two technical replicates with similar results

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