Table 2 Different gene expression profile between TREM2 overexpression MHCC97H and the control
Gene name | Description | Fold change | P | NCBI gene_ID |
---|---|---|---|---|
Increased expression > 2.5-fold | ||||
CDH1 | Cadherin 1, type 1, E-cadherin (epithelial) | 4.23 | <0.01 | NM_004360 |
OPCML | Opioid binding protein/cell adhesion molecule-like | 3.87 | <0.05 | NM_002545 |
RELN | Reelin | 3.38 | <0.05 | NM_005045 |
IGFBP1 | Insulin-like growth factor binding protein 1 | 2.72 | <0.01 | NM_000596 |
CTNNB1 | Catenin (cadherin-associated protein), beta 1 | 2.66 | <0.01 | NM_001904 |
PTEN | Phosphatase and tensin homolog | 2.62 | <0.05 | NM_000314 |
TNFSF10 | Tumor necrosis factor (ligand) superfamily, member 10 | 2.53 | <0.01 | NM_003810 |
Decreased expression > 2.5-fold | ||||
HGF | E74-like factor 3 (ets domain transcription factor, epithelial-specific) | 3.76 | <0.05 | NM_000601 |
AKT1 | V-akt murine thymoma viral oncogene homolog 1 | 5.71 | <0.05 | NM_005163 |
IRS1 | Insulin receptor substrate 1 | 3.17 | <0.01 | NM_005544 |
TGFβ1 | sex determining region Y-box 15 | 2.69 | <0.05 | NM_000660 |