Table 2 Different gene expression profile between TREM2 overexpression MHCC97H and the control

From: TREM2 acts as a tumor suppressor in hepatocellular carcinoma by targeting the PI3K/Akt/β-catenin pathway

Gene name

Description

Fold change

P

NCBI gene_ID

Increased expression > 2.5-fold

CDH1

Cadherin 1, type 1, E-cadherin (epithelial)

4.23

<0.01

NM_004360

OPCML

Opioid binding protein/cell adhesion molecule-like

3.87

<0.05

NM_002545

RELN

Reelin

3.38

<0.05

NM_005045

IGFBP1

Insulin-like growth factor binding protein 1

2.72

<0.01

NM_000596

CTNNB1

Catenin (cadherin-associated protein), beta 1

2.66

<0.01

NM_001904

PTEN

Phosphatase and tensin homolog

2.62

<0.05

NM_000314

TNFSF10

Tumor necrosis factor (ligand) superfamily, member 10

2.53

<0.01

NM_003810

Decreased expression > 2.5-fold

HGF

E74-like factor 3 (ets domain transcription factor, epithelial-specific)

3.76

<0.05

NM_000601

AKT1

V-akt murine thymoma viral oncogene homolog 1

5.71

<0.05

NM_005163

IRS1

Insulin receptor substrate 1

3.17

<0.01

NM_005544

TGFβ1

sex determining region Y-box 15

2.69

<0.05

NM_000660