Table 1 Analysis of DHA effect in PCa cell lines

From: Dihydroartemisinin inhibits prostate cancer via JARID2/miR-7/miR-34a-dependent downregulation of Axl

Cell line

IC50 ± SD (µM)

95% Confidence interval

DU145

4.8 ± 0.89

3.49–6.96

PC-3

5.1 ± 0.91

2.75–5.41

C4

3.9 ± 0.45

2.78–4.46

C4-2

4.9 ± 0.52

3.07–5.75

C4-2B

5.1 ± 0.55

3.59–5.86

LNCaP

22.1 ± 1.89

15.2–30.5

  1. A dose-response curve was performed and inhibition of proliferation was analyzed. IC50 = 4.8 µM in DU145; 5.1 µM in PC-3; 3.9 µM in C4, 4.9 µM in C4-2, 5.1 μM in C4-2B and 22.1 μM in LNCaP