Fig. 6: CDCA5 knockdown suppresses tumor growth in vivo. | Oncogenesis

Fig. 6: CDCA5 knockdown suppresses tumor growth in vivo.

From: Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway

Fig. 6

A xenograft nude mouse model was used to investigate the effect of CDCA5 knockdown on tumor growth. HCT116 or HT-29 cells were transduced with sh-CDCA5 or sh-Ctrl lentivirus, and then injected subcutaneously into BALB/c nude mice. a Average tumor volume from day 5 after injection (lower panel; *P < 0.05 vs. sh-Ctrl). b Representative images of fluorescence (upper panel) and GFP intensity (lower panel; *P < 0.05 vs. sh-Ctrl) were observed at the end of experiments. c Representative images of tumor (upper panel) was observed and average tumor weight (lower panel) were assessed (*P < 0.05 vs. sh-Ctrl group)

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