Fig. 3: Transcriptional consequences and prognostic associations of TP53 splice mutations.
From: Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
a TP53 gene expression levels according to mutation type. Due to small sample sizes, in frame indels and silent mutations were not included. b TP53 signature score according to mutation type. Due to small sample sizes, in frame indels and silent mutations were not included. ssGSEA single-sample gene set enrichment analysis. c Kaplan−Meier survival curve showing 5-year relapse-free survival (RFS) for patients with TP53 wt, exon mutations and splice mutations in CRC stage II. d 5-year RFS according to TP53 mutation type in CRC stage II. Due to small sample size, in frame indels and silent mutations (N = 1) were not included
