Fig. 1: BRG1 regulates lung cancer cell proliferation and migration.

a–h Gene expression levels in human lung cancer specimens are examined by qPCR. i, j LLC cells were exposed to 1% O2 and harvested at indicated time points. Gene expression levels were examined by qPCR and Western. k, l LLC cells were transfected with HA-tagged BRG1 or an empty vector (EV) before exposure to 1% O2 for 24 h. MTT assay and wound healing assay were performed and quantified as described in Methods. m, n LLC cells were transfected with siRNA targeting BRG1 or scrambled siRNA (SCR) before exposure to 1% O2 for 24 h. MTT assay and wound healing assay were performed and quantified as described in Methods