Fig. 5: SCUBE3 knockdown may not induce caspase-dependent apoptosis in U251 cells.
From: Reduction of SCUBE3 by a new marine-derived asterosaponin leads to arrest of glioma cells in G1/S
a Golgi swelling and endoplasmic reticulum swelling were observed in SCUBE3-knockdown U251 (pointed by arrows) under TEM; b a PathScan Stress and Apoptosis Signaling Antibody Array Kit was used for overall detection of 18 signaling molecules in down-shSCUBE3-transfected U251 cells. The expression level was calculated relative to the positive control signal as a gray value (n = 3, *p < 0.05, **p < 0.01 compared with blank-shctrl group).
