Fig. 5: The expression of genes in the SQS/OPN axis is correlated with poor survival among patients with lung cancer.
From: Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway
a Kaplan–Meier analysis of overall survival (left) and survival to the first progression (right) among patients with lung cancer is achieved by examining the combination of SQS and OPN mRNA expression levels. other: SQS low/OPN high and SQS high/OPN low. b Kaplan–Meier analysis of the overall survival (left) and disease-free survival (right) in 126 patients with lung cancer stratified according to SQS and OPN protein levels. c Left, Representative images of SQS and OPN IHC staining in serial sections of lung cancer tissues derived from patients. Right, Quantification of SQS and OPN IHC staining in lung cancer tissues. N = number of specimens. **P, < 0.01. Scale bar: 100 μm. d Kaplan–Meier analysis of overall survival (left) and disease-free survival (right) in 126 patients with lung cancer stratified according to the SQS and OPN protein levels.
