Fig. 1: The high expression level of HMGB1 in triple-negative breast cancer patients is associated with tumor metastasis. | Oncogenesis

Fig. 1: The high expression level of HMGB1 in triple-negative breast cancer patients is associated with tumor metastasis.

From: Tumor-derived HMGB1 induces CD62Ldim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer

Fig. 1

a GEO database correlation analysis of HMGB1 expression with overall survival (OS), Relapse-free survival (RFS) and distance metastasis free survival (DMFS) in basal-like breast cancer patients. b TCGA database and METABRIC database analysis of HMGB1 expression in basal-like and non-basal-like breast cancer. c Representative images of HMGB1 staining scoring criteria in breast cancer. d The HMGB1 staining scores in triple-negative breast cancer (TNBC) and Non-TNBC. e The HMGB1 staining scores in primary breast cancer with and without lung metastasis for 10 years. f Elisa analysis of serum HMGB1 concentration in breast cancer patients with different molecular types. Data are mean ± SEM of one representative experiments. Similar results were seen in three independent experiments unless noted otherwise. Unpaired Student’s t tests, ns not significant. *p < 0.05, **p < 0.01, ***p < 0.001. See also Fig. S1.

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