Fig. 4: RNF187 reversely correlates with Hippo/YAP signaling in TBNC tumor samples. | Oncogenesis

Fig. 4: RNF187 reversely correlates with Hippo/YAP signaling in TBNC tumor samples.

From: Regulation of Hippo signaling and triple negative breast cancer progression by an ubiquitin ligase RNF187

Fig. 4

a Kaplan–Meier graph of progression-free survival shows that RNF187 relates to poor prognosis in all breast cancer patients. b Kaplan–Meier graph of progression-free survival shows that RNF187 relates to poor prognosis in ER positive breast cancer patients. c Kaplan–Meier graph of progression-free survival shows that RNF187 tends to relate to good prognosis in triple negative breast cancer patients. d Kaplan–Meier graph of progression-free survival shows that YAP relates to poor prognosis in triple negative breast cancer patients. e, f Public available data shows that RNF187 is reversely correlated with Hippo/YAP target genes: CTGF and CYR61 (https://www.cbioportal.org). g Example tumor cases showing that RNF187 reversely correlates with YAP protein in IHC. h Statistical analysis of RNF187 correlation with YAP in forty TNBC tumor samples.

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