Fig. 7: The hypothetical model for RNF187 regulating Hippo signaling in triple negative breast carcinoma.

RNF187 protein associated with YAP and promoted YAP degradation via inducing YAP K48-linked poly-ubiquitination.

RNF187 protein associated with YAP and promoted YAP degradation via inducing YAP K48-linked poly-ubiquitination.