Fig. 1: Carbidopa inhibits LNCaP cell proliferation and migration. | Oncogenesis

Fig. 1: Carbidopa inhibits LNCaP cell proliferation and migration.

From: Carbidopa suppresses prostate cancer via aryl hydrocarbon receptor-mediated ubiquitination and degradation of androgen receptor

Fig. 1

a, b Colony formation assay in human PCa cell lines: LNCaP (a) and DU145 (b) cells were cultured in the presence of increasing doses of Carbidopa for 2 weeks and stained 0.1% crystal violet. c LNCaP and DU145 cells were treated with increasing doses of Carbidopa for 24 h, and the cell viability was examined by MTT assay. d Colony formation assay in human PCa cell lines: VCAP and PC3 cells were cultured in the presence of increasing doses of Carbidopa for 2 weeks and stained 0.1% crystal violet. e VCAP and PC3 cells were treated with increasing doses of Carbidopa for 24 h, and the cell viability was examined by MTT assay. f Migration assay analysis LNCaP cells with or without Carbidopa. g Quantitative analysis of cell migration in at least three separate fields; data are given as means ± SEM. *p < 0.05 versus control. h Migration assay analysis DU145 cells with or without Carbidopa. i Quantitative analysis of cell migration in at least three separate fields; data are given as means ± SEM.

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