Fig. 4: Gene expression profiles and genetic instability of induced gall bladder (GB) cancers. | Oncogenesis

Fig. 4: Gene expression profiles and genetic instability of induced gall bladder (GB) cancers.

From: Precision modeling of gall bladder cancer patients in mice based on orthotopic implantation of organoid-derived tumor buds

Fig. 4

A RNA-seq analysis using the orthotopic GB cancer tissues, GBCa-#1, #2, and #3, and normal GB tissues, GB-#1, #2, #3. The network layout of pathway enrichment analysis is shown. The size of each circle node is proportional to the number of input genes that fall under that term. Terms with a similarity score >0.3 are linked by an edge. Top 20 statistically enriched terms are shown with their p value. Log10(P), the p value in log base 10. MTC microtubule cytoskeleton. IL interleukin. B Summary of genome instability. Gene copy number alteration was calculated based on whole-genome analysis of GBCa-#1 is shown. Green, red and blue dots indicate base line, gain, and loss, respectively. Chr chromosome.

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