Fig. 6: CIC-DUX4 induces H3 acetylation that is reversible by iP300w. | Oncogenesis

Fig. 6: CIC-DUX4 induces H3 acetylation that is reversible by iP300w.

From: Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma

Fig. 6

A Immunostaining for CIC-DUX4 in the 3T3-CIC-DUX4 cell line. B RT-qPCR for CIC-DUX4 and its target genes in 3T3-CIC-DUX4 cells treated for 18 h with iP300w. C Western blots for ETV4 and acetylated H3K18 and H3K27 in 3T3-CIC-DUX4 cells treated for 18 h with iP300w. D Western blots for H3 acetylation markers in CIC-DUX4 sarcoma cell lines treated for 18 h with iP300w.

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