Fig. 6: INS-p25OE PanNETs form successful allografts.
From: Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors
A Photograph from IVIS image of representative allograft tumor model; tumor marked with yellow arrow. B Photograph and fluorescence imaging from IVIS, ex vivo, of kidney (left) and tumor (right) from representative allograft model. C Penetrance in primary INS-p25OE model (P0), passage 1 models (P1), and passage 2 models (P2). D Tumor onset in the same groups as C (P0, n = 21; P1, n = 5; P2, n = 5). E Fold growth of passage 1 tumors over a 5 week period starting at ~100 mm3 (week 0) (weeks 0–3, n = 6; weeks 4–5, n = 5). F H&E stains and immunostains of primary INS-p25OE model (P0) and three passage 1 models (P1a-c).
