Fig. 5: Integrative view of GNMT regulation in prostate cancer. | Oncogenesis

Fig. 5: Integrative view of GNMT regulation in prostate cancer.

From: PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer

Fig. 5

Schematic representation of Methionine cycle, Polyamine metabolism, and PI3K-mTOR axis interaction. PIP2 phosphatidylinositol 4,5-bisphosphate, PIP3 phosphatidylinositol 3,4,5-trisphosphate, PDK1 Phosphoinositide-dependent kinase 1, TSC tuberous sclerosis protein complex, RHEB Ras homolog enriched in brain, Gly Glycine.

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