Fig. 4: Overexpression of DDX3X promoted proliferation in subcutaneous xenograft models, while knockdown of DDX3X induced the opposite effects. | Oncogenesis

Fig. 4: Overexpression of DDX3X promoted proliferation in subcutaneous xenograft models, while knockdown of DDX3X induced the opposite effects.

From: DDX3X interacts with SIRT7 to promote PD-L1 expression to facilitate PDAC progression

Fig. 4

A The study, which included eight mice per group, analyzed the weight, volume, and representative images of H&E staining of subcutaneous xenograft tumors. B Representative tumor sections stained for DDX3X (IHC). C Representative tumor sections stained for Ki67 (IHC). D Tumor weight, tumor volume and the images of H&E staining of the tumors (n = nine mice per group). Data are shown as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001. p values were calculated by Student’s t test.

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