Fig. 5: Overexpression of DDX3X promoted proliferation in orthotopic xenograft models, and knockdown of DDX3X induced the opposite effects.
From: DDX3X interacts with SIRT7 to promote PD-L1 expression to facilitate PDAC progression
A Representative images of H&E staining of orthotopic xenograft tumors (n = five mice per group). B Representative tumor sections stained for DDX3X (IHC). C Representative tumor sections stained for Ki67 (IHC). D Representative images of H&E staining of the tumors (n = six mice per group). Data are shown as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001. p values were calculated by Student’s t test.
