Fig. 7: Knocking down SIRT7 reversed DDX3X-induced PDAC proliferation.
From: DDX3X interacts with SIRT7 to promote PD-L1 expression to facilitate PDAC progression
A The weight and volume of subcutaneous xenograft tumors (n = five mice per group). B Representative images of H&E staining of the tumors. C Images of orthotopic xenograft tumors (n = four mice per group). D Representative images of H&E staining of the tumors. E Western blotting was conducted to validate the efficiency of overexpression of DDX3X and knockdown of SIRT7. Cell proliferation ability was evaluated using colony formation assays.
