Table 2 Upstream regulators and relative predicted modulation based on fluid biomarkers functional analysis by IPA.
From: Proteomic meta-analysis unveils new frontiers for biomarkers research in pancreatic carcinoma
Upstream regulators | Molecular type | Predicted activation state | Activation z-score |
|---|---|---|---|
LPS | Chemical drug | Activated | 4.168 |
TNF | Cytokine | Activated | 3.998 |
P38-MAPK | Group | Activated | 2.853 |
AGT | Growth factor | Activated | 2.83 |
Tetradecanoylphorbol acetate | Chemical drug | Activated | 2.571 |
miR-323-5p (and other miRNAs w/seed GGUGGUC) | Mature microRNA | Inhibited | −2.345 |
miR-34a-5p (and other miRNAs w/seed GGCAGUG) | Mature microRNA | Inhibited | −2.646 |
