Fig. 2: Cells in the most advanced pEMT state express features of leader cells. | Oncogenesis

Fig. 2: Cells in the most advanced pEMT state express features of leader cells.

From: TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids

Fig. 2

A Expression of a custom leader cell gene expression profile was scored with SCANPY. The obtained leader cell scores were projected onto the UMAP. B UMAP cluster-specific visualization of leader cell scores in violin plots. C Expression of exemplary leader cell genes visualized in the UMAP space. The color scales represent the normalized counts (Norm. counts) of the indicated genes.

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